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Learn More About P. Murali Doraiswamy
Brains are not failing us because people are living longer. They are failing because modern organizations still think about brain health as a late-life issue rather than a leadership issue. Dr. P. Murali Doraiswamy argues that the same forces reshaping work — artificial intelligence, constant cognitive overload, longer careers, and rising rates of burnout — are also redefining what it takes to sustain peak performance.
Professor of Psychiatry and Professor in Medicine at Duke University School of Medicine, Doraiswamy is one of the world’s leading physician-scientists studying the future of brain health, cognitive resilience, and human performance.
Doraiswamy’s work sits at the intersection of neuroscience, aging, and artificial intelligence. He has spent decades studying why some people and organizations maintain clarity, adaptability, and resilience under pressure while others decline. His research on neurocognitive disorders and Alzheimer’s disease has helped shape many of the diagnostic tools, clinical trials, and therapeutics now used in modern medicine. Increasingly, however, he focuses on what business leaders need to know before decline begins: how to build cognitive resilience, strengthen decision-making, and create workplaces that support sustained performance in an era of rapid technological change.
For executive audiences, Doraiswamy offers a distinctly practical message: the future of leadership depends on understanding the future of the human mind. He examines how AI will augment — and in some cases compete with — human cognition, and why organizations that invest in wellbeing, focus, and mental fitness will outperform those that continue to treat brain health as a personal issue rather than a strategic priority. His emerging work on “digital cognitive twins” and precision psychiatry gives leaders a glimpse into how AI-driven models may soon predict stress, burnout, and cognitive decline before they become organizational problems.
Murali Doraiswamy also brings unusual authority to conversations about aging workforces, healthcare, and longevity. In “The Alzheimer’s Action Plan: The Experts’ Guide to the Best Diagnosis and Treatment for Memory Problems” (2008), he translated leading-edge science into a practical roadmap for patients and families. Today, he helps healthcare systems, financial institutions, technology companies, and global employers think more broadly about what it means to protect human capability in a world where people will work longer, think alongside machines, and face unprecedented cognitive demands.
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Dr. P. Murali Doraiswamy is a Professor of Psychiatry and Behavioral Sciences and Professor in Medicine at Duke University School of Medicine, where he directs the Neurocognitive Disorders Program and serves as a senior fellow at the Duke Center for the Study of Aging and Human Development. He is Co-Chair of the World Economic Forum Global Future Council on Mental Health, a Fellow of the Royal College of Physicians in London, and a Fellow of the American Neurological Association. Doraiswamy has authored more than 400 scientific publications, advised organizations including the National Institutes of Health, the Food and Drug Administration, and the World Health Organization, and his work has been featured by the BBC, The New York Times, TIME, PBS, and Oprah.
Dr. P. Murali Doraiswamy is available to advise your organization via virtual and in-person consulting meetings, interactive workshops and customized keynotes through the exclusive representation of Stern Speakers & Advisors, a division of Stern Strategy Group®.
Wellbeing as a Driver of Peak Performance
How to Cognitively Thrive in the AI Era
Human Brain vs Machine Brain
Longevity AI and the Future of the Mind

The Alzheimer's Action Plan: The Experts' Guide to the Best Diagnosis and Treatment for Memory Problems
(St. Martin's Press, April 2008)
Individual bioenergetic capacity as a potential source of resilience to Alzheimer’s disease
(Nature Communications, February 24 2025)

Digital therapeutics for mental health: Is attrition the Achilles heel?
(Frontiers in Psychiatry, 2022)
Mobile and pervasive computing technologies and the future of Alzheimer’s clinical trials
(Nature, NPJ Digital Medicine, 2018)

Neuroimaging assessment of early and late neurobiological sequelae of traumatic brain injury: implications for CTE
(Frontiers in Neuroscience, 2015)










